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Multiple drug companies have recently withdrawn their respective PARP inhibitors for heavily pretreated ovarian cancer patients, citing data showing an increased risk for death. In a September 14 letter to healthcare professionals, GlaxoSmithKline (GSK) announced the voluntary withdrawal of niraparib (Zejula) for fourth-line treatment in adults with advanced ovarian, fallopian tube, or primary peritoneal cancer
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This year, I stopped doing surgery — giving up the knife, so to speak. It wasn’t an easy decision to make. I’ve been a surgeon for 32 years since graduating from medical school. It’s been a distinct part of who I am for most of my life. This doesn’t mean I’ve retired. I’m still practicing
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An important message for former smokers: You can overcome a history of vice through virtue. People with a history of smoking who exercise regularly, eat nutritious foods, and maintain a healthy weight can reduce their risk for premature death by almost 30% compared with those who don’t adopt such good habits, researchers have found.  “Engaging
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The Centers for Disease Control and Prevention (CDC) said this week that based on the latest data on pregnancy-related deaths in the U.S., about 80% of the cases were actually preventable.  The public health agency published Monday the data on 1,018 pregnancy-related deaths among residents of 36 states from 2017-2019 collected through the Maternal Mortality
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Randomized comparisons of percutaneous coronary intervention (PCI) and coronary bypass surgery (CABG) for left-main coronary disease, including those that have sparked very public debate, naturally enrolled patients suitable for either procedure. But that takes a toll on their relevance to clinical practice, where patients are not so narrowly defined. It also highlights the role of
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The American Academy of Sleep Medicine (AASM) issued a health advisory Wednesday encouraging parents to seek medical advice before giving melatonin or any supplement to children. “While melatonin can be useful in treating certain sleep-wake disorders like jet lag, there is much less evidence it can help healthy children or adults fall asleep faster,” M.
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A recent study in The Lancet Global Health takes a pessimistic view of our ability to eradicate measles by 2100, although rubella forecasts look a bit more promising. So far, measles has been eliminated in 81 countries and rubella in 93. But factors such as antivaccination sentiment and misinformation linking vaccination to autism have led to
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Having trouble sleeping can leave you exhausted and sleepy in the morning, affecting your mood, performance, sleeping habits, and overall well-being. Although difficulty sleeping isn’t always a cause for alarm; it could still result in deeper problems like sleep apnea, restless legs syndrome, or narcolepsy, especially if not managed properly.  Difficulty sleeping is commonly caused
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New Haven, Connecticut — Sing “Happy Birthday”? Recite the ABCs? Count 20 seconds? What’s the best way to ensure the effectiveness of hand washing? Maintaining good hand hygiene practices remains key to preventing the spread of pathogens in the healthcare setting and beyond. However, hand hygiene habits have long proven resistant to change among healthcare
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